Research on Coronaviruses

The following projects are concerned with biological aspects of coronaviruses and with preclinical and clinical questions relating to coronavirus infections.

List of funded Projects:

Subject Area Project in GEPRIS
Structural Biology
Funded in 2020
Structural Biology of SARS-CoV-2 by NMR spectroscopy (Covid19-NMR) (B18)
Metabolism, Biochemistry and Genetics of Microorganisms
Funded in 2018
Characterization of SARS-CoV-2 isolates and functional studies of viral virulence in human lung organoids (A07*)

Agriculture, Forestry and Veterinary Medicine
Funded in 2013

Virology Funded in 2013:

Virology Funded between 2013 to 2021:

SFB 1021: RNA Viruses: RNA Metabolism, Host Response and Pathogenesis

Regulation of RNA metabolism, translation and protein degradation pathways in the host response to coronavirus infection (C02)

Pathogenesis of feline infectious peritonitis (B01)

Agriculture, Forestry and Veterinary Medicine
Biology Funded between 2013 to 2020

Virology Funded between 2013 to 2017:

Virology Funded between 2016 to 2020:

Utilization of spatially resolved data sources for an established agent-based model of Germany and its impact on predicted SARS-CoV-2 dynamics

Phylogenetic and experimental reconstruction of zoonotic transmission of human coronaviruses

Role of importin-alpha isoforms in MERS-Coronavirus interspecies transmission and subsequent infection of the human respiratory tract

Funded between 2014 to 2016
Surface glycoproteins of two bat paramyxoviruses: functional characterization and importance for host switch
Ecology and Biodiversity of Animals and Ecosystems, Organismic Interactions
Funded between 2014 to 2018
Coronaviruses as a paradigm for the transmission interface between wildlife, livestock and humans

Funded in 2016

Clinical Infectiology and Tropical Medicine Funded in 2016:

Clinical Infectiology and Tropical Medicine Funded in 2016:

KFO 309: Virus-induced Lung Injury: Pathobiology and Novel Therapeutic Strategies

Targeting immunophilin- and MAPK-associated pathways to inhibit MERS-CoV replication and prevent lung injury

Virus-Host interactions that drive and control respiratory epithelial injury in coronavirus infections

Parasitology and Biology of Tropical Infectious Disease Pathogens
Funded in 2020
Identification of factors influencing zoonotic transmission of MERS-Coronavirus in Kenya