Dr. Thimoteus Speer
© T. Speer
Nephrology, Saarland University
Lipid metabolism disorders are one of the key risk factors for arteriosclerotic changes to the arteries, which can cause strokes and heart attacks. However, not all blood lipids are harmful. Thimoteus Speer has demonstrated that only certain modified lipids have a damaging effect on arteries in people with kidney disease. Crucially, he linked these findings with newly discovered processes of chronic inflammation and was able to explain certain mechanistic details of this fatal interaction. He therefore made an important link between these two common damage processes. Speer’s findings have made it possible to establish diagnostic precision medicine and, in the medium term, the development of new treatment strategies. The importance of his work is therefore due to its strong translational research approach. Working from the basis of a joint doctorate in human medicine and biology, he has conducted outstanding basic and translational research. This is reflected in his roles as senior physician, laboratory director for experimental and translational nephrology, and project leader in a DFG-funded Collaborative Research Centre.