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Information für die Wissenschaft Nr. 3 | 4. Januar 2017
E-Rare Call for Proposals 2017: Transnational Research Projects for Innovative Therapeutic Approaches for Rare Diseases

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) as partner of the ERA-Net for Research Programmes on Rare Diseases (E-Rare) is pleased to announce the 2017 call for proposals on “Transnational Research Projects for Innovative Therapeutic Approaches for Rare Diseases”.

Background

The ERA-Net for research programmes on rare diseases (E-Rare) has been established to help in coordinating the research efforts of European countries in the field of rare diseases and implement the objectives of International Rare Disease Research Consortium (IRDiRC). The DFG is a funding partner among 20 parties that have decided to open the 9th E-Rare joint transnational call (JTC 2017) for funding multinational research projects on rare diseases.

Scope

The aim of the call is to enable scientists in different countries to build an effective collaboration on a common interdisciplinary research project based on complementarities and sharing of expertise, with a clear translational research approach. Projects shall involve a group of rare diseases or a single rare disease following the European definition i.e. a disease affecting not more than five in 10.000 persons in the European Community, EC associated states and Canada.

The specific objective of this call is to promote research projects focussing on the pre-clinical development of therapeutic approaches in suitable existing animal or cell models.

Therapeutic approaches can include:

  • cell-based therapy (e.g. somatic cell therapy, cell-based regenerative medicine, tissue engineering, therapies based on combination of cells with scaffolds or substrates, etc.)
  • gene therapy (e.g. transfer of nucleic acids for therapeutic purposes including DNA, RNA, oligonucleotides, etc.)
  • pharmacological therapy (e.g. use of chemicals or biopharmaceuticals including repurposing approaches, high throughput screening of molecules, etc.)

Project proposals must clearly demonstrate the potential health impact as well as the added-value of transnational collaboration: gathering a critical mass of patients/biological material, sharing of resources (models, databases, diagnosis, etc.), harmonisation of data, sharing of specific know-how and/or innovative technologies, etc.

The following approaches are excluded:

  • therapeutic approaches concerning rare infectious diseases, rare cancers and rare adverse drug events in treatments of common diseases
  • interventional clinical trials or any other interventional treatment of patients within the project (e.g. compassionate use)
  • the set-up of new patient registries/databases
  • development of new cell or animal models; the relevant cell or animal model must be already established for the purpose of the project
  • surgery or radiation therapies

Deadlines

There will be a two-stage submission procedure for joint applications: pre-proposals and full proposals. In both cases, one joint proposal document (in English) shall be prepared by the partners of a joint transnational proposal, and must be submitted to the Joint Call Secretariat (JCS) by uploading it on the electronic submission system by one spokesperson, the coordinator.

Joint pre-proposals (in English) must be received by the JCS in an electronic version no later than 1 February 2017 at 5 p.m.

Please note that joint full proposals will be accepted only from those applicants who were explicitly invited by the JCS to submit them. Full proposals (in English) must be received by the JCS in an electronic version no later than 2 June 2017 at 5 p.m.

Further information on how to submit pre-proposals and full proposals electronically are made available through the E-Rare website (www.erare.eu) and in the guidelines for applicants. The forms that have to be used for submission of pre-proposals and full proposals are available on the E-Rare website.

Further Information

Detailed information and the guidelines for applicants are available on the E-Rare website:

Please be aware that the eligibility requirements in form 50.01 (Guidelines for the DFG Research Grants Programme) will apply for German partners. The guideline can be found at:

Contact person at the DFG:

For general questions relating to the call or the online application system please contact the E-Rare call secretariat:

Zusatzinformationen

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